Description
T4 (Levothyroxine) 40mcg 100 tablets core introduction *
Pharmaceutical-grade formulation | STROMUSC brand T4 (Levothyroxine) oral tablets (Levothyroxine Sodium Tablets )
Chemical name : L-3,3′,5,5′-Tetraiodothyronine sodium salt
CAS No .: 55-03-8
Specifications : 40mcg/tablet, 100 tablets/bottle
Dosage form : Film-coated tablets
Molecular formula : C₁₅H₁₀I₄NNaO₄
Molecular weight : 798.86
Appearance : White, round, film-coated sheet, engraved with the STROMUSC logo and dividing lines.
Purity : ≥99% (HPLC detection)
Storage conditions : Store at 15-25℃, protected from light, with humidity ≤60%.
T4 (Levothyroxine) Core Function | Core Effects
STROMUSC brand levothyroxine sodium is a long-acting thyroid hormone replacement therapy . Due to its stable blood drug concentration and good tolerability , it is widely used for basic treatment, metabolic regulation and long-term hormone replacement of hypothyroidism .
✅Triple physiological effects :
Basal metabolic regulation : Maintaining a normal basal metabolic rate
Growth and development : Promotes normal growth and development
Thermoregulation : Maintaining normal body temperature and energy metabolism
✅ STROMUSC brand quality advantages :
Precise micro-dose : 40mcg precise dosage, content uniformity RSD ≤ 2.0%
Dissolution stability : Dissolution rate ≥85% within 15 minutes.
China cGMP Production : Production strictly adheres to China’s cGMP standards.
✅Quality assurance advantages :
Purity Guarantee : Raw material purity ≥ 99.5%, conforming to USP standards.
Stability optimization : Antioxidant coating technology, with a shelf life of up to 24 months.
Anti-counterfeiting system : Holographic anti-counterfeiting label, QR code for full traceability
Brand Quality Advantages
1. Raw material quality control :
Chemical purity : Raw material purity ≥ 99.5% (chiral HPLC detection)
Optical purity : L-configuration optical purity ≥ 99.8%
Iodine content : 63.5-65.5%, meeting pharmacopoeia standards.
2. Advantages in formulation technology :
Micronization technology : Raw material particle size D90≤5μm, ensuring uniform absorption.
Multi-layer coating :
Isolation layer: Anti-oxidation and moisture protection
Enteric coating: Delays release and improves bioavailability
Precise dosage : Weight variation of 40mcg tablets ≤ ±2%
3. Production Quality System :
cGMP Certification : China’s cGMP Certified Production Facilities
Environmental control : 20-25℃, 45-55% constant temperature and humidity workshop
Quality Traceability : A Full-Process Electronic Traceability System from Raw Materials to Finished Products
4. Quality control indicators :
Content uniformity : RSD ≤ 2.0% (Pharmacopoeia requirement ≤ 6%)
Dissolution rate : ≥85% dissolution at 15 minutes, ≥90% dissolution at 30 minutes.
Related substances : Degradation products <0.1%, total impurities <0.2%
Stability : Passed accelerated testing after 6 months; shelf life: 24 months.
T4 (Levothyroxine) Application Features and Advantages
1. Efficacy characteristics :
Long-lasting and stable : Half-life of approximately 7 days, with stable blood drug concentrations.
Physiological replacement : It is converted into T3 in the body and exerts physiological functions.
Mild onset of action : Stable treatment response with relatively mild side effects.
Long-term safety : Suitable for long-term thyroid replacement therapy
2. Key Features and Advantages :
Standardized production : standardized dosage, stable quality between batches.
Convenient to use : once daily administration, high compliance.
Monitoring clearly shows that TSH is a well-defined indicator for monitoring treatment efficacy.
Price and Economy : More cost-effective compared to other thyroid medications
3. Advantages of use :
Flexible dosage adjustment : Multiple dosage specifications to meet individual needs
Long-term treatment : Suitable for patients requiring long-term thyroid replacement.
Combination therapy : Can be used in combination with other thyroid medications.
T4 (Levothyroxine) Oral Administration Guide
1. Standard usage :
Starting dose : 25-50 mcg daily for adults, taken as a single dose.
Maintenance dose : Adjust to 50-200 mcg daily based on TSH levels.
Timing of administration : It is recommended to take it on an empty stomach in the morning, at least 30 minutes before breakfast.
Dosage : Swallow the tablet whole with plenty of water; do not chew.
2. Individualized solutions :
Adult hypothyroidism : Start with 25-50 mcg/day, adjust every 4-6 weeks.
For older adults : Start with 12.5-25 mcg/day, gradually increasing the dose.
Hypothyroidism in children : Calculated based on body weight, 2-4 mcg/kg per day.
During pregnancy : The dosage needs to be increased by 20-30%, and regular monitoring is required.
3. Precautions for use :
Take on an empty stomach : Take on an empty stomach in the morning, avoid taking with food.
Avoid interfering with : Avoid taking with calcium supplements, iron supplements, antacids, or high-fiber foods.
Take medication at the same time every day to maintain a stable blood drug concentration.
Monitoring timing : Check TSH levels at least 6 weeks after starting medication.
Dosage adjustment : Adjust by 12.5-25 mcg each time, slowly.
4. Special Population Programs :
For patients with heart disease : Start with a dose of 12.5-25 mcg/day, increasing slowly.
Renal insufficiency : No dose adjustment required.
Hepatic insufficiency : Generally no dose adjustment is required.
Elderly patients : Start with a low dose, increase slowly, and adjust every 6-8 weeks.
5. Dosage Adjustment Guidelines :
TSH > 10 mIU/L : Increase by 25-50 mcg/day
TSH 5-10 mIU/L : Increase by 12.5-25 mcg/day
TSH normal range : Maintain current dose
TSH < 0.1 mIU/L : Reduce by 12.5-25 mcg/day
6. Precautions for combined medication :
Combined use with T3 : can correct symptoms more quickly; FT3 and FT4 need to be monitored.
Other medications : Be aware of interactions with anticoagulants, antidepressants, etc.
Effects of supplements : Note that calcium and iron supplements may reduce absorption rates.
Disease impact : Patients with malabsorption syndrome require increased dosage.
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